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Which should be more reactive for an SN2 reaction involving sodium iodide in a solution of acetone, 2-chlorobutane or 2-bromobutane?
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- PHENOL: what effect and orientation does –OH group exhibit in electrophilic aromatic substitution reaction?which will proceed more easily at room temperature the bromination of cyclohexene or the bromination of benzene?Possible alternative brominations include: Veratrole (1,2-dimethoxybenzene) to 1,2-dibromo-4,5-dimethoxybenzene; 4-Methylacetanilide to 2-bromo-4-methylacetanilide; 2-Methylacetanilide (made in experiment S.1) to 4-bromo-2-methylacetanilide; Vanillin to 5-bromovanillin; Acetanilide to 4-bromoacetanilide; a. b. C. d. e. EXPERIMENT S4: BROMINATION OF AROMATIC COMPOUNDS Certain other acetanilides made in experiment S.1 may also be used as precursors in this experiment. Estimated time: 1 afternoon Associated learning goals: Section 6, LG 6.6; Section 7, LG 7.2 and 7.4 Pre-lab report: complete the standard report form, and answer the following questions. In this experiment, molecular bromine (Br2) is generated from the redox reaction of potassium bromate with hydrobromic acid. Write a balanced equation for this process. Briefly outline the mechanism by which Br2 brominates your aromatic compound. Why do the bromine atoms end up at the positions indicated rather than anywhere else in the…
- Joshua, an organic chemistry student, successfully performed a nucleophilic substitution reaction in the lab using2-bromo-2-methylpropane and methanol. The professor asked the student to repeat the experiment but increase the rateof the reaction by a factor of 4. How would the student achieve an increase in the rate of the reaction when performingthe experiment again?9:09 Question 10 of 20 Done Predict reagents needed to complete this SN1 solvolysis reaction. Br CH3OH AWhat are the organic products of these reactions? Are they electrophiles or nucleophiles? What is their decreasing order of rate?