Why is bond B longer than bond A in the given protonated epoxide?

Q: Which N in DBU compound acts to accept a proton in an E2 reaction and why?

A: DBU is  Diazabicycloundecene. It is a Nucleophilic, bulky base. It is Stable, water-soluble, and…

Q: Which reaction product (A or B) is more likely to form in the epoxide ring opening reaction?…

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Q: `NH HNO3 `NH H2SO4 NO2 Acetanilide para-Nitroacetanilide

A: We have to draw the curly arrow mechanism for this reaction showing step by step and also draw two…

Q: Need help providing a mechanism for the formation of C from A.

A: In this question, we will draw the mechanism for the formation of C from A  You can see details…

Q: Where will a nucleophile initially bond to the structure of carvone, provide a reason

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Q: Draw the two intermediates, including resonance structures, for the attack of nitronium ion on…

A: The substitution reactions of aromatic rings in which an atom in the ring is replaced by the…

Q: Rank the following according to increasing reactivity with 1 as the least reactive, and 4 as the…

A: The reactivity order for nucleophilic acyl substitution is as follows:

Q: Draw the reactivity series for nucleophilic substitution at the carbonyl carbon. (You may exclude…

A: Reactivity series for nucleophilic substitution at the carbonyl carbon?

Q: For each pair, predict the stronger nucleophile in the SN2 reaction (using an alcohol asthe…

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Q: 8. Propose an efficient synthesis of for each of the following transformation: a) b) EtO OEt

A: Many reagents are used for the conversion of one compound to another. A chemical reaction takes…

Q: What nucleophile would be required to effect the following reactions?

A: a) aqueous NaOH or aqueous KOH Nucleophilic substitution reaction (SN2 mechanism)  b) NaOCH3 (sodium…

Q: This reaction is an example of conjugate addition of a nucleophile to an a,ß-unsaturated carbonyl.…

A: The two resonance structures of the enolate anion intermediate for this reaction can be drawn as…

Q: List A-D in order of increasing ability of a nucleophile to displace a leaving group in a…

A: a) & b)  Aqueous acetone is a protic solvent (the water H-bonds tightly to F-) so iodide will…

Q: Draw the major E2 elimination product formed from the attached alkylhalide.

A: The E2 elimination mechanism involves the abstraction of beta-proton by base and removal of halide…

Q: Attached compounds undergoes E2 elimination with strongbase? For compounds that undergo elimination,…

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Q: Is a intramolecular Friedel Crafts acylation reaction. As you from the product, the acylation…

A: Applying concept of organic synthesis and reagent.

Q: Can 2,4-pentanedione undergo an intramolecular aldol addition? If so, why? If not, why not?

A: Aldol addition in organic chemistry is a chemical reaction in which an enol or an enolate ion…

Q: Draw the product of the reaction and explain the reason OMe

A: Pericyclic reactions are proceeds by a cyclic shift of electrons by a single-step reaction…

Q: (disconnect to a "diketone" (a) (b) (c) starting material)

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Q: Explain why compound A does not undergo an E2 elimination with strong base.

A: For the structure to be more stable it has to have the bulky phenyl group in the equtorial position.…

Q: Draw the major product(s) of nitration of benzoic acid.

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Q: How can this product be synthesized via a Michael reaction.

A: Addition of active CH group at α,β-unsaturated carbonyl, cyano, ester, nitro compounds in basic…

Q: What neutral nucleophile is needed to convert dihalide A to ticlopidine, an antiplatelet drug used…

A: The ticlopidine is framed by supplanting one of the Cl with a nucleophile.  Also, the nucleophile…

Q: Draw a stepwise, detailed mechanism for the attached intramolecular reaction.

A: The mechanism of the reaction is as follows: Step-1: A pair of pi electrons of double bond abstracts…

Q: Which ester, C or D, is more reactive in nucleophilic acyl substitution?Explain your reasoning.

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Q: Which of the listed conditions and nucleophile/s will open the epoxide at carbon A? Which will open…

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Q: Explain why the C=C of an enol is more nucleophilic than the C=C of an alkene, despite the fact that…

A: The electron pair availability or nucleophilicity depend upon the two factors: 1. Resonance 2.…

Q: LDA is the base of choice for carbonyl compound to completely convert into enolate. Why?

A: The full form of LDA is Lithium diisopropylamide. It has isopropyl groups create hindrance and make…

Q: Why is the carbon bonded to halogen electrophilic? Indicate with arrows the direction of…

A: Carbon is less electronegative than halogen atom.  Halogen atom has greater tendency to attract…

Q: What is/are the proper descriptor(s) of the product of the following reaction? HN and trace acid O…

A: Ro answer this question , we would first write the product of the reaction. Then we can check the…

Q: Identify the stronger nucleophile in each pair of anions. a.Br− or Cl− in a polar protic solvent…

A: A nucleophile is an electron rich species which consists of lone pair of electron pair or pi bond to…

Q: Explain the major step of a nucleophilic acyl substitution ?

A: The functional groups that undergo nucleophilic acyl substitutions are called carboxylic acid…

Q: 7. Propose an efficient synthesis of for each of the following transformation: a) b)

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Q: List TWO nucleophiles that would react with the epoxide belowwith the opposite regioselectivity…

A: Epoxides - Epoxide is an cyclic ether. The 3 membered ring unstable due to ring strain. The C-O…

Q: Complete the mechanism for the base-catalyzed opening of the epoxide by adding any missing atoms,…

A: Epoxides are reactive, methoxide ion attacks the Epoxides in a less sterically hindered position…

Q: 1. Why is aldol product the major product in relation to the Cannizzaro reaction?

A: Note: Since you have posted a question with multiple subparts, we will solve the first three…

Q: What are the nucleophilic strengths in descending order of the nucleophiles in protic and aprotic…

A: A good nucleophile is the one that can donate lone pair of electrons.

Q: Draw the organic product of the following nucleophilic substitution reaction. (Assume that only…

A: Given reaction,

Q: Arrange in decreasing order according to their reactivity towards an electrophile. H A В

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Q: Explain why aprotic conditions favor a kinetic enolate ?

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Q: please explain the mechanism of ring opening of an epoxide by reaction with nucleophile under acidic…

A: The reactions of Epoxides with strong nucleophiles requires a strong driving force that helps in the…

Q: Which of the following reaction yields a carbonyl-containing product?   a Ozonolysis   b Mild…

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Q: Identify the stronger nucleophile in the following pair of anions. HS− or F− in a polar protic…

A: A nucleophile has an electron density that can be donated.

Q: Use the curved arrow formalism to draw the complete mechanism for the Claisen condensation reaction…

A: The solution is as follows :

Q: Draw the three intermediates, including resonance structures, for the attack of nitronium ion on…

A: The given reaction is the nitration of pyridine. The substitution can occur at three positions,…

Q: Azulene, an isomer of naphthalene, having fused 5 and 7 membered rings, has the following orbital…

A: Azulene: It is non-benzenoid fused ring system in which 5-membered and 7-membered ring systems are…

Aldehydes and Ketones

Aldehydes and ketones are organic compounds that have a carbonyl group, C = O, as their functional group. They both differ in the placement of this carbonyl group in their structures.