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- The omicron variant of SARS-CoV-2 has the amino acid substitution G339D in the spike protein on the virus surface. In cellular fluids at -pH 7 the wild type spike protein has a net negative charge. This substitution will make the spike protein: less negative absorb UV light more strongly at 280 nm more negative more hydrophobicAnswer the following and inlcude the references SARS-CoV-2, the virus that causes CoVid-19, belongs to the Coronaviridae family. Viruses under this family have a genome made of single-stranded positive-sense RNA. Is this similar to the viral genome of HIV? If so, do you think that – in theory – they would have similar replication cycles? Do you think that ART combinations/options might help in suppressing the viral replication of SARS-CoV-2? Expound.of Poxviruses are unusual among DNA viruses because their replication cycles takes place entirely in the host cell cytoplasm. How can these viruses carry out genome replication and transcription of viral genes without going to the nucleus? Briefly explain. Edit View Insert Format Tools Table 20px v Paragraph v へ へ ヘ .V8:11 EEO 1I0 & %24 9 6 n d k 4
- Indicate whether the following sentences is either True or False and CORRECT the wrong sentences ( please answer the two questions 1 and 2) : 1. Simian Virus 40 (SV40) is an example of is a circular ssDNA belong to Polyomavirus, was first isolated from primary cell cultures derived from rhesus monkey kidneys, and activates p53. 2. SARS-COV-2 is an enveloped, icosahedral virus that is surrounded by a lipid bilayer and causes COVID-19 pandemic .The complete coronavirus genome sequence from the first known patient infected with SARS-CoV-2 was published on January 10th 2020, just a short time after the patient had been hospitalized in China with respiratory symptoms. They did this so quickly using nanopore sequencing. Scientists compared the genome sequence from the new coronavirus (SARS-CoV-2) with the genome sequences from several other coronaviruses and they did identify a sequence unique to the SARS-CoV-2 strain. This unique sequence was in the N gene of the viral genome. What protein is made from the N gene of the virus?Answer the two questions below by reading the article 1, What was discovered in this article and how is it interesting 2, How is this discovery in the article related to genetics Article The novel SARS-CoV-2 coronavirus that emerged in the city of Wuhan, China, last year and has since caused a large scale COVID-19 epidemic and spread to more than 70 other countries is the product of natural evolution, according to findings published today in the journal Nature Medicine. The analysis of public genome sequence data from SARS-CoV-2 and related viruses found no evidence that the virus was made in a laboratory or otherwise engineered. "By comparing the available genome sequence data for known coronavirus strains, we can firmly determine that SARS-CoV-2 originated through natural processes," said Kristian Andersen, PhD, an associate professor of immunology and microbiology at Scripps Research and corresponding author on the paper. In addition to Andersen, authors on the paper, "The proximal…
- Match the terms 1Genome surrounded by a protein coat 2Functional viral particle capable to infect a new host cell 3Infectious protein 4Infectious agent that needs helper virus for infection 5T4 enzyme that creates holes in the E. coli plasma membrane 6When a temperate phage stimulates their bacterial host tostart producing a toxin (e.g. cholera, shiga) 7Virus that infects bacteria 8Hand N spikes 9Virus without an envelope 10Most common and best studies virulent phage of E. coli 11Protein coat that surrounds viral genome 12:true or false : some viruses can cause cancer [ Choose ] lambda True pathogenic stimulation False Nucleocapsid lysosome Naked virus induction lysozyme Flu viruses tobacco mosaic virus lysogeny capsid Lysogenic conversion Holin Prion satellite bacteriophage (or just phage) T4 Virion StreptococcusSyn5 is a virus that infects photosynthetic bacteria belonging to the genus Synechococcus. The Syn5 virion is icosahedral (660 Å in diameter) with a short tail and an appendage called a horn. The horn is located on a vertex directly opposite the tail. Syn5 follows the typical five steps observed for most viruses when they multiply, and progeny viruses are released when the host lyses. The assembly of Syn5 virions involves several proteins, including capsid proteins, scaffolding proteins, a portal protein, a terminase, tail proteins, and horn proteins. To better understand the assembly of Syn5 virions, scientists used a type of microscopy called Zernike phase contrast electron cryotomography. This type of microscopy improves the contrast typically seen for conventional cryotomography. In their studies, the scientists observed several different developing virus particles in infected cells. The particles were: (1) 660 Å icosahedron containing DNA and having a tail; (2) 660 Å icosahedron…This figure shows the frequency of the different variants of the novel coronavirus over time colored as each variant. I need help understanding what the figure tells me about the relative fitnesses of the delta variant compared to the alpha variant?
- Research has found that 95% of the particles smaller or equal to the size of the COVID-19 virus will not penetrate through a mask. Based on molecular characteristics of surface molecules of the virus, why might this be?Compare and contrast the role and types of viral mutations in 1918 IAV and SARS-C0V-2 in the respective pandemics, paying particular attention to: 1. causes of mutations 2. Key mutations responsible for generating highly pathogenic viral strain. 3. effects of mutated viral gene products on host immune system. 4. effects of newly emergent viral strain on virus spread worldwide.Which of the following is NOT true about the current coronavirus global pandemic (COVID- 19)? O Laboratory diagnosis of infection is based on polymerase chain reaction (PCR) testing of patient samples for RNA from the causative virus Nucleic acid vaccines to prevent COVID- 19 (and/or its most severe forms) are authorized for use in the US Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Person-to-person transmission can occur through respiratory secretions (droplets and/or aerosols) None of the other four answers (All are true about COVID-19