Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 12.1, Problem 1COMQ
Which of the following base sequences is used during transcription?
a. Promoter and terminator
b. Start and stop codons
c. Ribosome-binding site
d. Both a and b
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Which of the following is/are not necessary for transcription to occur?
A. Promoter region B. Terminator region C. Start codon D. Stop codon
Which of the following mutations is most likely to cause a single amino acid difference during the translation of mRNA into protein?
A. Single base-pair insertion
B. Single base-pair deletion
C. Mutations in regulatory sites
D. Base-pair substitution
Which of the following statements are NOT true?
A. Replication is the process of making DNA and takes place in the nucleus of prokaryotic cells.
B. Translation produces a polypeptide that may require additional processing to become a functional protein
C. Transcription starts at the promoter of eukaryotic cells and scans until reaches the start codon.
D. Splicing results in exons being put together and introns being removed
Chapter 12 Solutions
Genetics: Analysis and Principles
Ch. 12.1 - 1. Which of the following base sequences is used...Ch. 12.1 - Prob. 2COMQCh. 12.2 - With regard to a promoter, a transcriptional start...Ch. 12.2 - Prob. 2COMQCh. 12.2 - 3. Sigma factor is needed during which stage(s) of...Ch. 12.2 - A uracil-rich sequence occurs at the end of the...Ch. 12.3 - Which RNA polymerase in eukaryotes is responsible...Ch. 12.3 - Prob. 2COMQCh. 12.3 - Prob. 3COMQCh. 12.3 - Prob. 4COMQ
Ch. 12.4 - Which of the following are examples of RNA...Ch. 12.4 - A ribozyme is a. a complex between RNA and a...Ch. 12.4 - Prob. 3COMQCh. 12.4 - Prob. 4COMQCh. 12.5 - 1. Which of the following is not a key difference...Ch. 12 - Prob. 1CONQCh. 12 - Prob. 2CONQCh. 12 - Prob. 3CONQCh. 12 - Prob. 4CONQCh. 12 - 5. Mutations in bacterial promoters may increase...Ch. 12 - Prob. 6CONQCh. 12 - 7. In Chapter 9, we considered the dimensions of...Ch. 12 - 8. A mutation within a gene sequence changes the...Ch. 12 - Prob. 9CONQCh. 12 - At the molecular level, describe how factor...Ch. 12 - Prob. 11CONQCh. 12 - What is the complementarity rule that governs the...Ch. 12 - 13. Describe the movement of the open complex...Ch. 12 - 14. Describe what happens to the chemical bonding...Ch. 12 - Prob. 15CONQCh. 12 - Prob. 16CONQCh. 12 - Prob. 17CONQCh. 12 - Mutations that occur at the end of a gene may...Ch. 12 - If the following RNA polymerases were missing from...Ch. 12 - 20. What sequence elements are found within the...Ch. 12 - 21. For each of the following transcription...Ch. 12 - 22. Describe the allosteric and torpedo models for...Ch. 12 - Which eukaryotic transcription factor(s) shown in...Ch. 12 - 24. The initiation phase of eukaryotic...Ch. 12 - A eukaryotic protein-encoding gene contains two...Ch. 12 - 26. Describe the processing events that occur...Ch. 12 - Prob. 27CONQCh. 12 - Prob. 28CONQCh. 12 - Prob. 29CONQCh. 12 - Prob. 30CONQCh. 12 - 31. In eukaryotes, what types of modifications...Ch. 12 - Prob. 32CONQCh. 12 - Prob. 33CONQCh. 12 - 34. Figure 12.21 shows the products of alternative...Ch. 12 - 35. The processing of ribosomal RNA in eukaryotes...Ch. 12 - Prob. 36CONQCh. 12 - Prob. 37CONQCh. 12 - After the intron (which is in a lariat...Ch. 12 - Prob. 1EQCh. 12 - 2. Chapter 21 describes a technique known as...Ch. 12 - Prob. 3EQCh. 12 - As described in Chapter 21 and in experimental...Ch. 12 - Prob. 5EQCh. 12 - Prob. 6EQCh. 12 - 1. Based on your knowledge of introns and pre-mRNA...Ch. 12 - Discuss the types of RNA transcripts and the...
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- The codon and anticodon are base-paired together during the process of translation. Which of the following is correct regarding the relationship between anticodon and codon? A. The tRNA anticodon UCU pairs with the AGA mRNA codon. B. The tRNA anticodon is read from the 5’ to the 3’ end. C. A tRNA anticodon can pair with only one mRNA codon. D. The mRNA codon ACG base pairs with the tRNA anticodon TGC.arrow_forwardGiven is the 30 nucleotides in the human gene for hemoglobin (the oxygen-carrying protein in the red blood cells): 5’ TAC-CAC-GTG-GAC-TGA-GGA-CTC-CTC-TTC-AGA 3’ a. What is the complementary strand? b.Deduce the mRNA in this coding region. c.What is the amino acid sequence based on this mRNA? d. A very important mutation in human hemoglobin occurs in this DNA sequence, where the T at nucleotide 20 is replace with an A. The mutant hemoglobin is called sickle cell hemoglobin and is associated with severe anemia. What is the amino acid replacement that results in sickle-cell hemoglobin?arrow_forwardGiven is the 30 nucleotides in the human gene for hemoglobin (the oxygen-carrying protein in the red blood cells): 5’ TAC-CAC-GTG-GAC-TGA-GGA-CTC-CTC-TTC-AGA 3’a. What is the complementary strand?b. Deduce the mRNA in this coding region.c. What is the amino acid sequence based on this mRNA?d. A very important mutation in human hemoglobin occurs in this DNA sequence, where the T at nucleotide 20 is replace with an A. The mutant hemoglobin is called sickle cell hemoglobin and is associated with severe anemia. What is the amino acid replacement that results in sickle-cell hemoglobin?arrow_forward
- Which of the following are steps of transcription? Select all that apply. a.RNA polymerase assembles a strand of mRNA complementary to the noncoding strand of DNA. b.RNA polymerase binds to a gene’s promoter. c.RNA polymerase assembles a strand of mRNA complementary to the coding strand of DNA. d.RNA polymerase moves over the gene and unzips the double helix to form a “transcription bubble.”arrow_forwardWhich of the following are steps of transcription? Select all that apply. A. RNA polymerase binds to a gene’s promoter. B. RNA polymerase moves over the gene and unzips the double helix to form a “transcription bubble.” C. RNA polymerase assembles a strand of mRNA complementary to the coding strand of DNA. D. RNA polymerase assembles a strand of mRNA complementary to the noncoding strand of DNA.arrow_forwardWhich of the following is an RNA processing event that increases the number of potential polypeptides that can be encoded by a single gene. a. transcription b. alternative splicing c. alternative transcription d. polyadenylationarrow_forward
- During initiation of translation, a is positioned first at the start codon. A. fMet-tRNA B. Val-tRNA C. Cys-tRNA D. Ser-tRNAarrow_forwardWhy might a single base-pair mutation in eukaryotic mRNA be less serious than one in prokaryotic mRNA? a. If the mutation occurs in the 5' end of the start site, it will not affect the gene product. b. If the mutation occurs in the exon, it will not affect the gene product. c. If the mutation occurs in the splice site of a transcript with alternative splicing, only one gene product may affected. O d. If the mutation occurs in the intron or not in the splice site of a transcript with alternative splicing, it will nc affect the gene product. O e. If the mutation occurs in the 3' end of the start site, it will not affect the gene product. OLIE STIC N 1Aarrow_forwardWhat factors are utilized by the cell in order to recognize the stop codon and disassemble the translation machinery? A. elongation factors B. release factors C. transcription factors D. initiation factors E. mRNA factorsarrow_forward
- The release factors RF1 and RF2 are required for a. translation termination b. the realease of the aminoacid from the tRNA c. translation elongation d. translation initiationarrow_forwardTranscription in prokaryotes produces mRNA that is ready to translate, while in eukaryotes the RNA must be processed by... A. Adding a 5' cap, which is a version of a guanine nucleotide B. Adding a 3' poly A tail, which is a series of adenosines C. Removing introns D. A and B E. A, B, and Carrow_forwardWhich of the following statements is/are TRUE for transcription? A. RNA polymerase uses one strand of DNA, the antisense strand, for RNA synthesis. B. The first ribonucleotide binds to the Pribnow region. C. RNA polymerase moves from 5’ → 3’, while the RNA polymerization is from 3’ → 5’. D. All four ribonucleoside monophosphates are required.arrow_forward
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