Consider the structure below. Which of the following structures are not expected to be found in blood or urine after its administration H₂N HN- NH₂ Option 1 NH₂ None -NH₂ ! HN- H₂N NH₂ NH₂ None -NH₂ Option 2 Option 3 NH₂
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- Based on the following titration table of Glycine, would you be able to recreate the same for Histidine? Glicina Increasing pH H-N-CH,-COOH -H-N-CH,-co = H-N-CH,-C00- Net charge: +1 pH COOH-pKa = 2.3 NH3-pka = 9.6 CN AEq +1 +1 2.3 (0.5°-1)+(0.5°0)=-0.5 +0.5 0.5 9.6 -1 (0.5*+1)+(0.5°0)=+0.5 -0.5 1.5 14 Given that the pKas for Histidine are the following: pka1 = 1.82 pKa2 = 9.17 pКаз %3 6.00 pL = 7.59 2.NH3* *H3N Give the abbreviation for the above tripeptide using the three-letter codes for each amino acid. Z-エ の エ-ZThe PI of protein P is 7.3. One can purify protein P by: Anion-exchange chromatography at pH 2.0 Anion-exchange chromatography at pH 7.3 Anion-exchange chromatography at pH 9.0 Anion-exchange chromatography at pH 4.3
- Draw the stereoisomers of the following amino acids. Indicate pairs of enantiomers and pairs of diastereomers. leucineCH3CHCH2 CHCOO−CH3 +NH3 isoleucineCH3CH2CH CHCOO−CH3Name the following molecular: CH3-CH2-CH2-CH2-CH2-CH-OHIn the space provided, draw a Haworth projection for the beta anomer of the following monosaccharide Fischer projection. CHO HO-C-H HO-C-H HO-C-H H-C-OH CH,OH
- Η Η Ο Η Η H | || | | H,N-C-C-N-c-coo + H₂N OH ΝΗ,Shown below is the structure of guanine. -NH N NH₂ -N H Draw the potential tautomers of guanine. Explain the potential risk of guanine (enol form) during S phase. (i) (ii) N ΙΖLefer to the figure showing the molecular structure of dimethylmercury. H–C-Hg C-H H. Exposure of human skin to a single drop of dimethylmercury can lead to death, as it is highly poisonous and passes easily cell membranes. Based on its structure, why is it able to pass so easily through cell membranes? I-0-I IICIH
- Using the generic structure shown, indicate what the substituents are for the structure of finerenone (R1, R2, R3, for Ar indicate R6, R8, R9, R10, for D indicate R4). R1 R2 R3 = For Ar: R6 R8 = R9 = R10 = For D: R4= Finerenone: H₂N HC Generic formula: H₂N 230 R+ 'R'. R$ ofGiven this: Protein Isoelectric pH Molecular weight (kDa) Ovalbumin 4.6 45 Insulin 5.4 5.7 Fibrinogen 5.8 340 Y-globulin 6.6 160 Collagen 6.6 115 Hemoglobin (monomer) 7.1 16 Myoglobin 7.0 16.7 Does all proteins separated properly using SDS page?Identify the selected functional groups inside of the red dotted lines.