3. Based on the stomach empty model, the liquid empty process follows first-order kinetics, while the digestible solid empty process follows zero-order kinetics. a) If we know the rate constant for liquid empty k = 6 × 104/s, please compute the half-life t1/2 of gastric emptying for this liquid. b) At time t = 3 × 1/2, i.e. triple the half-life, what percentage of gastric volume is still filled with the liquid? c) How long does it take to reduce the percentage of gastric volume filled with liquid to 5%? d) If we know the rate constant for digestible solid empty ks = 1.5 × 10-4/s, and the lag phase is 45 min, please compute the total time required for fully emptying the digestible solid.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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3. Based on the stomach empty model, the liquid empty process follows first-order kinetics, while
the digestible solid empty process follows zero-order kinetics.
a) If we know the rate constant for liquid empty k = 6 × 104/s, please compute the half-life t1/2 of
gastric emptying for this liquid.
b) At time t = 3 × 1/2, i.e. triple the half-life, what percentage of gastric volume is still filled with
the liquid?
c) How long does it take to reduce the percentage of gastric volume filled with liquid to 5%?
d) If we know the rate constant for digestible solid empty ks = 1.5 × 10-4/s, and the lag phase is 45
min, please compute the total time required for fully emptying the digestible solid.
Transcribed Image Text:3. Based on the stomach empty model, the liquid empty process follows first-order kinetics, while the digestible solid empty process follows zero-order kinetics. a) If we know the rate constant for liquid empty k = 6 × 104/s, please compute the half-life t1/2 of gastric emptying for this liquid. b) At time t = 3 × 1/2, i.e. triple the half-life, what percentage of gastric volume is still filled with the liquid? c) How long does it take to reduce the percentage of gastric volume filled with liquid to 5%? d) If we know the rate constant for digestible solid empty ks = 1.5 × 10-4/s, and the lag phase is 45 min, please compute the total time required for fully emptying the digestible solid.
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