A crossed Claisen reaction between methylpropanoate and methyl acetate is not synthetically useful because it produces a mixture of products. The reaction between methyl 2-methylpropanoate and methyl acetate, however, is synthetically useful. Explain why. 1. CH;ONa, CH3OH Mixture of products O. 2. Н,О, НСІ Methyl propanoate 1. CH3ONA, CH3OH 2. НаО, НСІ Methyl 2-methylpropanoate 78%

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter11: Ethers, Epoxides, And Sulfides
Section: Chapter Questions
Problem 11.18P
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A crossed Claisen reaction between methylpropanoate and methyl acetate is not synthetically useful because it
produces a mixture of products. The reaction between methyl 2-methylpropanoate and methyl acetate, however, is
synthetically useful. Explain why.
1. CH;ONa, CH3OH
Mixture of products
O.
2. Н,О, НСІ
Methyl propanoate
1. CH3ONA, CH3OH
2. НаО, НСІ
Methyl 2-methylpropanoate
78%
Transcribed Image Text:A crossed Claisen reaction between methylpropanoate and methyl acetate is not synthetically useful because it produces a mixture of products. The reaction between methyl 2-methylpropanoate and methyl acetate, however, is synthetically useful. Explain why. 1. CH;ONa, CH3OH Mixture of products O. 2. Н,О, НСІ Methyl propanoate 1. CH3ONA, CH3OH 2. НаО, НСІ Methyl 2-methylpropanoate 78%
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