person consumes 100 micrograms of a tracer chemical. Assume that the person is able to collect all of the tracer in their urine (and therefore measure the amount that has come out of the body), as well as the concentration in the blood, as a function
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A person consumes 100 micrograms of a tracer chemical. Assume that the person is able to collect all
of the tracer in their urine (and therefore measure the amount that has come out of the body), as well
as the concentration in the blood, as a function of time (see table below).
c is the value of V that you determined equal to the blood volume of the person? Does this make
sense to you? If not, what does V represent?
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Solved in 2 steps
- Lisa Smith (LS) is brought to the emergency department [ER] for management of accidental acute poisoning. She is nonresponsive and admitted to the critical care unit [CCU] to be closely monitored. LS has no urinary output, and her laboratory values are serum K+ = 6.7 mEq/L; serum Na+ = 177 mEq/L; arterial blood gases [ABGs]: pH = 7.13, PaCO2 = 35 mmHg, HCO3- = 16 mEq/L, PaO2 = 89 mmHg, and oxygen saturation = 94%. What electrolyte disturbances need to be monitored at this time? What clinical signs & symptoms should the nurse be assessing LP, at this time, for the electrolyte disturbances?Table 3. Serum creatinine values at admission and after 12h Admission +12h SCR(mg/dL) 1.55 1.42 Using the “MDRD” (Modification of Diet in Renal Disease) equation for estimating glomerularfiltration, provided below, and the data available in the above table, calculate the patient's (a 34 year old white male) estimated glomerularfiltration rate (eGFR) at admission and 12h after admission.MDRD GFR Equation (mL/min/1.73 m2)= 175 × (Scr)-1.154 × (Age)-0.203 × (0.742 if female) × (1.212 if African American)Based on your calculated values, state whether LF’s function is normal or abnormal?Previous research suggests that patients with asthma have an increased risk for chronic kidneydisease, but the mechanisms underlying this increased risk are poorly understood. Propose one potential mechanism by which asthma might impair kidney function, and discuss how this dysfunction may impair thebody’s ability to respond to respiratory alkalosisIn reviewing the patient’s current information, a concern exists that acute kidney injury has developed. Select to highlight the laboratory information that would support this concern.UrinalysisCasts - +++Cola-color to urineProteinuriaBlood ValuesRBC - 3.9 cells/L (4.0-4.9 cells/L)Hgb 10 g/dL (12-16 g/dL)Hct-40% (37%-48%)WBC 11.0 cells/L (4.0-10.0 cells/L)Platelets - 140 cells/L (150-450 cells/L)Sodium - 140 mEq/L (135-145 mEq/L)Potassium - 4.5 mEq/L (3.5-5.2 mEq/L)BUN - 32 mg/dL (5-20 mg/dL)Creatinine 1.8 mg/dL (0.5-1.5 mg/dL)Blood Glucose - 180 mg/dL (nonfasting) (<200 mg/dL)AST-40 Units/mL (5-40 Units/mL)ALT - 30 Units/mL (5-35 Units/mL)Bilirubin (total)- 0.8 mg/dL (<1.0 mg/dL)Albumin - 4.0 (3.5-5.5 g/dL)PT-22 (11.5-14 seconds)
- Urine creatinine: 190 mg/dL .Plasma creatinine: 2.5 mg/dL. 24-hour urine collection: 975 mL. C(ml/min)= (U(mg/dL)x V(mL/min) )/(P(mg/dL))36. A 3-month-old boy is brought to the emergency department because of a 2-day history of lethargy. Physical examination shows no other abnormalities. The results of laboratory studies are shown: Serum Na+ 165 mEq/L (N=139-146) CI- 130 mEq/L (N=95-105) 334 mOsmol/kg H₂O (N=282-295) Osmolality Urine 1.001 Specific gravity Osmolality 117 mOsmol/kg H₂O (N>200) He is admitted to the hospital. His urine output is increased. His serum ADH (vasopressin) concentration is 24 pg/mL (N=1-5); aldosterone and renin concentrations are within the reference ranges. The urine osmolality remains unchanged after administration of 1-deamino-8-arginine vasopressin. An MRI of the brain and pituitary gland shows no abnormalities. Ultrasonography shows normal kidneys. The most likely underlying cause of the findings in this patient is a defect in which of the following? A) Angiotensin-converting enzyme B) Aquaporin C) 11a-Hydroxylase D) Renin E) Vasopressin receptorsWhat is the patient's creatinine clearance given the following data? Serum creatinine 0.6 mg/dL Urine creatinine 102 mg/dL 24 hr urine volume 1650 mL Patient's BSA 1.93 m2 1) 195 mL/min 2) 130 mg/dL 3) 93 mL/min 4) 175 mL/min no references, just homework
- Hematology Data: 24 hour urine volume: 1,000 mL; Serum Creatinine: 2.0 mg/dL; Urine Creatinine: 200 mg/dL What's the calculation for the Creatinine clearance? Please show steps, thank you!ICF and ECF are different names for the same material; O No answer text provided. O No answer text provided. O False O TrueA patient comes to your medical practice with complaints of low urine output (not peeing). You use inulin to calculate the glomerular filtration rate (GFR) using the following information: Plasma level (P – constant over 24 hours): 10 mg/mL inulin. Urine sample (U): 144 mg inulin/mL urine. Urine formation (V): 10 mL/min. Using the fromula GFR=V ✕ U/P, you calculate a GFR of ... A) 144mL/min.. B) 14400 mL/min. C) 144 min./mL. D) 144 g mannitol/min.
- Question 1 of 4 Match the following concepts to its respective indications. Match each item to a choice: Green Urine Black Urine Red Urine Dark Yellow Urine Colorless Urine Indication of Antihypertensive Drugs Recent Fluid Consumption Presence of high amounts of Erythrocytes Choices: Nosocomial Infection Excessive intake of anti-diureticsQuestion 4 of 4 Match the following pathological indications of urine turbidity. Match each item to a choice: WBCS Presence of Male Gamete RBCs Fungal Infection Bacterial Infection Presence of Lipid Metabolism Presence of Epithelial cells Choices: Increased amount of urine crystals Spermaturia Presence of lymphocytes or lymph fluidPatient A is 65 years old female. She has been diagnosed with diabetes Type II. Recently she experienced a gastrointestinal illness with nausea and vomiting. Lab data have been obtained the following day after her illness: Body weight 85 kg; Blood pressure 140/90 mmHg; Blood pH – 7.48; PCO2 – 44 mm Hg; Plasma HCO3 ion -32 mEq/L; Urine pH – 7.5. What is acid-base disorder of this patient. What was a main cause of this? The illness continues and after 2 days the following laboratory data have been obtained: Body weight 83 kg; Blood pressure 120/70 mmHg; Blood pH – 7.50; PCO2 – 48 mm Hg; Plasma HCO3 ion -36 mEq/L; Urine pH – 6.0. Has acid-base disbalance been changed? If yes, what is the explanation for this acid-base disbalance? Is there any compensation?
