Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 10.6, Problem 1COMQ
Summary Introduction
Introduction:
A chromosome is basically a deoxyribonucleic acid or DNA molecule which is containing either a part or all of the genetic material of the organism. Most of the eukaryotes have chromosomes which involves packaging of proteins that is aided by the chaperone proteins and binds to as well as condense the molecule of DNA to avoid it from becoming an unmanageable tangle.
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Which of the following represents the order of increasingly higher levels of organization of chromatin?
Select one:
O a. looped domain, nucleosome, 30-nm chromatin fiber
O b.
30-nm chromatin fiber, nucleosome, looped domain
C.
nucleosome, looped domain, 30-nm chromatin fiber
O d. looped domain, 30-nm chromatin fiber, nucleosome
nucleosome, 30-nm chromatin fiber, looped domain
е.
In the eukaryotic nucleus during interphase, a strand of chromatin consisting of eight conserved histone proteins, and a short region of double-stranded DNA wrapped around them, is:
A. properly referred to as the radial miniband
B. properly referred to as the supersolenoid
C. properly referred to as the chromosome
D. properly referred to as the nucleosome
E. properly referred to as the solenoid
The chromatin is composed of...
a. DNA (10%), RNA (30%), and histone proteins (60%)b. DNA (30%), RNA (30%), and histone proteins (40%)c. DNA (60%), RNA (30%), and histone proteins (10%)d. DNA (30%), RNA (10%), and histone proteins (60%)e. none of the above
Chapter 10 Solutions
Genetics: Analysis and Principles
Ch. 10.1 - 1. A bacterial chromosome typically contains
a. a...Ch. 10.2 - Mechanisms that make the bacterial chromosome more...Ch. 10.2 - 2. Negative supercoiling may enhance activities...Ch. 10.2 - 3. DNA gyrase
a. promotes negative supercoiling....Ch. 10.3 - 1. The chromosomes of eukaryotes typically contain...Ch. 10.4 - Which of the following is an example of a...Ch. 10.5 - What are the components of a single nucleosome? a....Ch. 10.5 - 2. In Noll’s experiment to test the...Ch. 10.5 - Prob. 3COMQCh. 10.5 - Prob. 4COMQ
Ch. 10.6 - Prob. 1COMQCh. 10.6 - 2. The role of cohesin is to
a. make chromosomes...Ch. 10 - Prob. 1CONQCh. 10 - Prob. 2CONQCh. 10 - 3. Describe the mechanisms by which bacterial DNA...Ch. 10 - Why is DNA supercoiling called supercoiling rather...Ch. 10 - Prob. 5CONQCh. 10 - Prob. 6CONQCh. 10 - Prob. 7CONQCh. 10 - Prob. 8CONQCh. 10 - Prob. 9CONQCh. 10 - 10. What is the function of a centromere? At what...Ch. 10 - Prob. 11CONQCh. 10 - 12. Describe the structures of a nucleosome and a...Ch. 10 - Beginning with the G1 phase of the cell cycle,...Ch. 10 - Draw a picture depicting the binding between the...Ch. 10 - 15. Compare heterochromatin and euchromatin. What...Ch. 10 - 16. Compare the structure and cell localization of...Ch. 10 - 17. What types of genetic activities occur during...Ch. 10 - Lets assume the linker region of DNA averages 54bp...Ch. 10 - 19. In Figure 10.12, what are we looking at in...Ch. 10 - 20. What are the roles of the core histone...Ch. 10 - A typical eukaryotic chromosome found in humans...Ch. 10 - Which of the following terms should not be used to...Ch. 10 - Discuss the differences between the compaction...Ch. 10 - 24. What is an SMC complex? Describe two...Ch. 10 - Two circular DNA molecules, which we can call...Ch. 10 - 2. Let’s suppose you have isolated DNA from a cell...Ch. 10 - 3. We seem to know more about the structure of...Ch. 10 - In Nolls experiment of Figure 10.11, explain where...Ch. 10 - When chromatin is treated with a salt solution of...Ch. 10 - 6. Let’s suppose you have isolated chromatin from...Ch. 10 - If you were given a sample of chromosomal DNA and...Ch. 10 - Consider how histone proteins bind to DNA and then...Ch. 10 - In Chapter 23, the technique of fluorescence in...Ch. 10 - Bacterial and eukaryotic chromosomes are very...Ch. 10 - The prevalence of highly repetitive sequences...Ch. 10 - Discuss and make a list of the similarities and...
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- After DNA replication, a eukaryotic chromosome _________ . a. consists of two sister chromatids b. has a characteristic X shape c. is constricted at the centromere d. all of the abovearrow_forwardThe compaction leading to a metaphase chromosome involveswhich of the following?a. The formation of nucleosomesb. The formation of the 30-nm fiberc. Anchoring and further compaction of the radial loopsd. All of the abovearrow_forwardChromosomes are visible under microscope during cell division because a. Thickening of chromatins b. Disappearance of the nucleoli c. Disintegration of the nuclear membrane d. Duplication of the DNAarrow_forward
- The role of the APC to get past the metaphase/ anaphase checkpoint is... Select one: a. to initiate gene expression of proteins involved in DNA replication. b. Add phosphates to the MPF to cause intermediate filaments to break down, free DNA to move in the cell. c. to add phosphate to intermediate filaments causing them to reform into the nuclear envelope d. add ubiquitin to cohesins allowing the sister chromatids to splitarrow_forwardWhich of the following statements is TRUE? Group of answer choices a Interphase chromosomes are loosely compacted and do not associate with histones until the cell is preparing to divide. b Interphase chromosomes are loosely compacted, overlapping, and intertwined with each other within the nucleus. c None of these are TRUE d Radial loops in the condensing chromosome are formed due to interactions between 30 nm fibers and the scaffolding proteins of the nuclear matrix - producing the 300 nm fiber of the chromosome e Interphase chromosomes are also known as euchromatin. Condensed, metaphase chromosomes are also known as heterochromatin.arrow_forwardA parent cell divides to form two genetically identical daughter cells in the process of mitosis. For mitosis to take place: A. the parent cell must divide its DNA in half so each daughter cell gets only the genes needed to carry out its functions. In this way, differentiation occurs. B. the parent cell must reproduce its DNA during telophase C. the parent cell must first be fertilized D. the parent cell must replicate its entire genome prior to mitosis E. crossover must be delayed until the second cell divisionarrow_forward
- Which of the following is responsible for moving chromosomes to the metaphase plate? A. Centromeres B. Cohesins C. Nuclear envelope D. Spindle microtubules 24.arrow_forwardThe nuclear matrix composition: a. lamina, nucleosome b. cortex, lamina, c. nucleosome d. lamina, interchromatin networkarrow_forwardThe interphase is the part of the eukaryotic cell cycle that is most transcriptionally active. Gene regulation during this phase involves changes in the chromatin. a.What is chromatin b.How can the chromatin structure be modiferied give ways and explainarrow_forward
- Which of the following does not contribute to genetic variation in sexually reproducing species? O a. random fertilization O b. independent assortment Oc cytokinesis O d. none of the answers are correct none of the answers are correct O e. crossing over All of the following correctly describe the sodium-potassium pump EXCEPT: O a. A total of five binding sites are present in the sodium-potassium pump O b. Potassium ions are pumped into the cell, where they are present in lower concentration than the extracellular fluid O c. The transport proteins will undergo some conformational changes O d. Molecules are pumped from low concentration to high concentration O e. Energy is required for the process to take placearrow_forwardWhich of the following statements about chromosomes and centromeres is INCORRECT?(choose the letter that corresponds to the answer) A. A centromere is a constriction visible on metaphase chromosomes. B. Centromere position is a useful marker for dividing chromosomes into karyotype groups. C. Centromeric protein-A replaces histone H3 in nucleosomes found at the centromere. D. Acentric and dicentric chromosomes are genetically stable chromosomes.arrow_forwardThe major event that occurs during the anaphase of mitosis, which brings about the equal distribution of chromosomes, is A Replication of the genetic material B Splitting of the chromatids C Splitting of the centromeres D Condensation of the chromatinarrow_forward
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