Anatomy & Physiology: An Integrative Approach
2nd Edition
ISBN: 9780078024283
Author: Michael McKinley Dr., Valerie O'Loughlin, Theresa Bidle
Publisher: McGraw-Hill Education
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Question
Chapter 12.6, Problem 16WDYL
Summary Introduction
To describe:
The three stages of voltage-gated
Concept introduction:
The unequal distribution of positive and negative charge across the cell membrane results in membrane potential of a cell. The rise and fall in the membrane potential of an axon in a specific location cause a series of electrical response or action potential.
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Describe the three states of voltage-gated Na+ channels in neurons.
Describe the action potential in terms of the different functional states of the voltage- gated Na+ membrane channels (Note: there are three states)
What determines the activity of the voltage-gated Na1 channel?
Chapter 12 Solutions
Anatomy & Physiology: An Integrative Approach
Ch. 12.1 - Prob. 1WDYLCh. 12.1 - What are the two primary functional divisions of...Ch. 12.2 - Prob. 3WDYLCh. 12.2 - Prob. 4WDYLCh. 12.2 - Prob. 5WDYLCh. 12.2 - Prob. 6WDYLCh. 12.2 - Prob. 7WDYLCh. 12.2 - What are the three connective tissue wrappings in...Ch. 12.3 - Prob. 9WDYLCh. 12.4 - If a person has a brain tumor, is it more likely...
Ch. 12.4 - Prob. 11WDYLCh. 12.4 - Prob. 12WDYLCh. 12.4 - Prob. 13WDYLCh. 12.5 - Prob. 14WDYLCh. 12.5 - Prob. 15WDYLCh. 12.6 - Prob. 16WDYLCh. 12.6 - Prob. 17WDYLCh. 12.7 - Prob. 18WDYLCh. 12.7 - Prob. 19WDYLCh. 12.7 - Prob. 20WDYLCh. 12.8 - How are EPSP and IPSP graded potentials...Ch. 12.8 - Prob. 22WDYLCh. 12.8 - How does depolarization and repolarization occur...Ch. 12.8 - Prob. 24WDYLCh. 12.8 - Prob. 25WDYLCh. 12.9 - Prob. 26WDYLCh. 12.9 - Prob. 27WDYLCh. 12.9 - Prob. 28WDYLCh. 12.9 - Prob. 29WDYLCh. 12.10 - Prob. 30WDYLCh. 12.10 - Prob. 31WDYLCh. 12.11 - Prob. 32WDYLCh. 12.11 - Prob. 33WDYLCh. 12 - _____ 1. The cell body of a neuron does all of the...Ch. 12 - Prob. 2DYKBCh. 12 - Prob. 3DYKBCh. 12 - Prob. 4DYKBCh. 12 - Prob. 5DYKBCh. 12 - Prob. 6DYKBCh. 12 - _____ 7. An action potential is generated when...Ch. 12 - Prob. 8DYKBCh. 12 - Prob. 9DYKBCh. 12 - Prob. 10DYKBCh. 12 - What are the four structural types of neurons? How...Ch. 12 - Prob. 12DYKBCh. 12 - How does myelination differ between the CNS and...Ch. 12 - Describe the procedure by which a PNS axon may...Ch. 12 - Prob. 15DYKBCh. 12 - Prob. 16DYKBCh. 12 - Explain summation of EPSPs and IPSPs and the...Ch. 12 - Graph and explain the events associated with an...Ch. 12 - Prob. 19DYKBCh. 12 - Prob. 20DYKBCh. 12 - Prob. 1CALCh. 12 - Prob. 2CALCh. 12 - Prob. 3CALCh. 12 - Prob. 4CALCh. 12 - Sarah wants to call her new friend Julie and needs...Ch. 12 - Over a period of 6 to 9 months, Marianne began to...Ch. 12 - Prob. 2CSLCh. 12 - Prob. 3CSL
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- Conformational changes in channel proteins brought about by voltage changes are responsible for opening and closing Na+ and K+ gates during the generation of an action potential. (True or false?)arrow_forwardAt the peak of an action potential, would the relative permeability of Na be higher than K? Which ion would be the least permeable to the membrane during falling phase?arrow_forwardDescribe two mechanisms by which ion channels are gatedarrow_forward
- Describe the contribution of each of the following to the establishment and maintenance of membrane potential: Part A Na+K+ Pump Passive movement of K+ across the membrane Passive movement of Na+ across the membrane Part B Resting membrane potential is approximately -70mV. Explain what resting membrane potential is and what -70mV refers to.arrow_forwardWhat is the expected resting membrane potential (in mV) of a neuron that is typical in all ways except for possessing an intracellular potassium concentration of 94 mM and double the normal resting permeability to sodium?arrow_forwardDefine the term voltage-gated ion channels?arrow_forward
- In the figure to the left, name the 4 phases of the action potential (Note: you have to write in where phase 4 occurs). Describe what happens in each phase with a focus on Na+ and K+ flow through channels and the membrane potential. Discuss the importance of threshold. How does this relate to the concept of APs being all or none?arrow_forwardAt which point in the graph do voltage-gated potassium channels open? (Base your answer to this question on the graph below depicting an action potential.) A B C D Earrow_forwardCompare the resting membrane potential of a neuron with the potassium and sodium equilibrium potentials. Explain how this comparison relates to the relative permeabilities of the resting plasma membrane to these two ions.arrow_forward
- Dendrotoxins, produced by the mamba snakes (Dendroaspis), are inhibitors of the voltage-gated K+ channels. What phase of the action potential would this toxin affect? How would it affect ion permeability during this phase? How would ion movement be affected?arrow_forwardAssume the membrane is only permeable to Na+ and K+, the electrical model of axon membrane is the following: Outside A INa gna ENa Ex D Inside The membrane potential at rest and at peak is -70mV and 45mV respectively; the potential of Sodium ion is 60mV and the potential of Potassium ion is -80mV. Find the ratio 9Na at rest and at peak. gKarrow_forwardWhy does neuronal function require the voltage-gated K+ channels to open moreslowly than the voltage-gated Na+ channels and how would you expect the voltage-gated K+ channels to affect the shape of an action potential curve?arrow_forward
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