Microbiology Fundamentals: A Clinical Approach
Microbiology Fundamentals: A Clinical Approach
3rd Edition
ISBN: 9781259709227
Author: Marjorie Kelly Cowan Professor, Heidi Smith
Publisher: McGraw-Hill Education
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Chapter 13, Problem 1Q

A single bacterium has _______ epitope(s).

  1. a. a specific
  2. b. multiple
  3. c. MHC
  4. d. clonal
Expert Solution & Answer
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Summary Introduction

Introduction:

The capacity of a lymphocyte to distinguish the difference between molecular shapes is so sensitive that it can recognize and respond to only a specific portion of an antigenic molecule. This fragment of the molecule is known as an epitope.

Answer to Problem 1Q

Correct answer:

A single bacterium has multiple epitopes. Therefore, option (b) is correct.

Option (b) is given as “multiple”.

Explanation of Solution

Justify the reason for the correct statement:

The epitope is an antigenic determinant fragment of an antigenic molecule. This is recognized by the immune system. It is the specific portion of antigen molecules and a single antigenic molecule carries multiple epitopes. Paratope is the portion of an antibody that binds to the antigenic epitope and trigger an immune response such as phagocytosis.

Hence, option (b) is correct.

Justify the reasons for the incorrect statements:

Option (a) is given as “a specific”.

Many epitopes are present on antigen molecules that generate specific immunity. Hence, it is a wrong answer.

Option (c) is given as “MHC”.

MHC stands for “major histocompatibility complex”. It is a surface marker that helps presentation of the pathogenic epitope to the T-cells. Hence, it is a wrong answer.

Option (d) is given as “clonal”.

Foreign antigen activates B or T cells that are appropriate (correct) for it by the mechanism of clonal selection. Hence, it is a wrong answer.

Hence, options (a), (c), and (d) are incorrect.

Conclusion

Multiple epitopes are found on a single bacterium.

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Chapter 13 Solutions

Microbiology Fundamentals: A Clinical Approach

Ch. 13.2 - Prob. 1MMCh. 13.2 - Prob. 2MMCh. 13.3 - List characteristics of antigens that optimize...Ch. 13.3 - Prob. 11AYPCh. 13.3 - Prob. 12AYPCh. 13.3 - Prob. 2NPCh. 13.4 - Prob. 13AYPCh. 13.4 - Explain how naive T cells become sensitized to an...Ch. 13.4 - Prob. 15AYPCh. 13.5 - Diagram the steps in B-cell activation, including...Ch. 13.5 - Prob. 17AYPCh. 13.5 - Explain the various end results of antibody...Ch. 13.5 - Prob. 19AYPCh. 13.5 - Draw and label a graphwith time on the horizontal...Ch. 13.6 - Prob. 21AYPCh. 13.6 - Discuss the qualities of an effective vaccine.Ch. 13.6 - Name the two major categories of vaccines and then...Ch. 13.6 - Explain the principle of herd immunity and the...Ch. 13.6 - 3. Which characteristic is associated with passive...Ch. 13 - A single bacterium has _______ epitope(s). a. a...Ch. 13 - Prob. 2QCh. 13 - Provide an explanation to refute the following...Ch. 13 - The primary B-cell receptor is a. IgD. b. IgA. c....Ch. 13 - Name three antigen-presenting cells, and what...Ch. 13 - Major histocompatibility molecules are critical...Ch. 13 - In humans, B cells mature in the ___ and T cells...Ch. 13 - Explain how the memory response is the cornerstone...Ch. 13 - Conduct research on clonal deletion and write a...Ch. 13 - Which of the following cells is capable of...Ch. 13 - Is antibody diversity generated at the DNA or RNA...Ch. 13 - In order for gene rearrangement of antigen...Ch. 13 - Prob. 13QCh. 13 - Prob. 14QCh. 13 - Using the details of T-cell activation, suggest a...Ch. 13 - A vaccine that contains parts of viruses is called...Ch. 13 - Explain how herd immunity works to protect the...Ch. 13 - Prob. 18QCh. 13 - Prob. 19QCh. 13 - Chronic lymphocytic leukemia leads to the...Ch. 13 - Prob. 21QCh. 13 - Prob. 1VC
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