Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
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Question
Chapter 14, Problem 23PIAT
Summary Introduction
To analyze:
The probability of the first child of the couple to have ALD (adrenoleukodystrophy).
Introduction:
Adrenoleukodystrophy is a type of X-linked disorder. It occurs as a result of mutation in the ABCD1 gene, which is present on the Xq28 chromosome. Furthermore, the nonfunctioning of these enzymes damages the myelin sheath present on the axon, which further causes degeneration of the neuron. In the given pedigree, the first daughter in the last generation is married to a man with no history of ALD in his family. Being a genetic counselor, advise the couple about chances of their first child having ALD. The pedigree is shown below:
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n the space below, use colored pencils to create a pedigree with the following information. Follow the guidelines for a
pedigree when creating this one.
Ray and Elaine were married in 1970. They both had normal vision. They had 2 daughters and then a son.
Both daughters, Alicia and Candace, had normal vision and never had any children of their own. The son, Mike, was
colorblind. The son married Beth who also had normal vision and they had 2 children of their own, first Greg then
Victoria. Victoria was colorblind, but Greg was not. Colorblindness is a sex-linked recessive trait.
Do not forget what shapes are male and female. Place the names and genotypes of the people under their shape.
Color your individuals the following:
Red- for colorblindness
White-for regular vision
Blue- for individuals with regular vision but are carriers
Green- unknown genotype
A family tree of sorts is called a pedigree. The symbols used for a pedigree are:
female, unaffected
female, affected
☐male, unaffected
male, affected
I
11
III
1
Pedigree Chart
Minor Peta #2
Siblings are placed in hirth order from left to right and are
labeled with Arabic numerals. Each generation is labeled
with a Roman numeral. Therefore, the male exhibiting the
trait in the pedigree below in the bottom, center would be
identified as III-4.
1. Which members of the family above are affected by Huntington's Disease?
4. How many girls did II-1 and 11-2 have?
3. How many children did individuals 1-1 and 1-2 have?
2. There are no carriers for Huntington's Disease- you either have it or you don't. With this in mind, is Huntington's disease
caused by a dominant or recessive trait?
5. How are individuals III-2 and II-4 related?
8
-Huntington's
Disease
A certain couple has six children – four boys (ages 2yr, 5yrs, 9yrs and 11yrs old) and two girls (ages 5yrs and 7yrs old). The oldest boy shows the symptoms of Duchenne Muscular Dystrophy (DMD). You are a geneticist and they come to you for advice. What would you tell them about the chances of their other children developing the disease?
Chapter 14 Solutions
Biological Science (7th Edition)
Ch. 14 - 1. The genes for the trails that Mendel worked...Ch. 14 - Example Problem Two black female mice are crossed...Ch. 14 - Prob. 5TYKCh. 14 - Prob. 6TYPSSCh. 14 - Prob. 7TYPSSCh. 14 - 11. In garden peas, yellow seeds (Y) are dominant...Ch. 14 - Prob. 9TYPSSCh. 14 - The smooth feathers on the back of the neck in...Ch. 14 - SOCIETY As a genetic counselor, you advise couples...Ch. 14 - 15. Suppose you are heterozygous for two genes...
Ch. 14 - Suppose a woman with blood type O married a man...Ch. 14 - Prob. 14TYPSSCh. 14 - Society Two mothers give birth to sons at the same...Ch. 14 - Prob. 16TYPSSCh. 14 - QUANTITATIVE Recall that hemophilia is an X-linked...Ch. 14 - Prob. 18PIATCh. 14 - Given the pedigree, what is the most likely mode...Ch. 14 - Prob. 20PIATCh. 14 - QUANTITATIVE If the son with ALD in the third...Ch. 14 - Prob. 22PIATCh. 14 - Prob. 23PIAT
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