Concept explainers
(a)
Interpretation:
The product formed on Aldol condensation in the given reaction is to be stated.
Concept introduction:
In Aldol condensation reaction, the base abstracts an acidic proton from the
(b)
Interpretation:
The product formed on Aldol condensation in the given reaction is to be stated
Concept introduction:
In Aldol condensation reaction, the base abstracts an acidic proton from the
(c)
Interpretation:
The product formed on aldol condensation in the given reaction is to be stated.
Concept introduction:
In Aldol condensation reaction, the base abstracts an acidic proton from the
(d)
Interpretation:
The product formed on aldol condensation in the given reaction is to be stated.
Concept introduction:
In Aldol condensation reaction, the base abstracts an acidic proton from the
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Organic Chemistry
- Propose a synthesis for each of the following compounds. (a) OH (b) (c)arrow_forwardFor the following structure, (a) propose the starting materials necessary to form it through an aldol reaction. (b) Identify the carbonyl electrophile, and the site of deprotonation for generation of the nucleophile to be used in the forward reaction. (Writing out the forward synthesis is not necessary.)arrow_forwardWhat reactant can be used to make this compound by an intramolecular aldol reaction? (A) (B) (C) (D) لسل Harrow_forward
- Predict the major products of the following base-catalyzed aldol condensations withdehydration.(a) benzophenone (PhCOPh) + propionaldehyde(b) 2,2@dimethylpropanal + acetophenonearrow_forwardWhat is meant by the following terms? Give an example of the reaction in each case.(i) Aldol (ii) Semicarbazonearrow_forward(a) Which of the following phenols is the least acidic? (b) Which of the following phenols is the most acidic?arrow_forward
- (a) What product is formed by the Claisen rearrangement of compound Z? (b) Using what you have learned about ring-closing metathesis in Chapter 26, draw the product formed when the product in part (a) is treated with Grubbs catalyst. These two reactions are key steps in the synthesis of garsubellin A, a biologically active natural product that stimulates the synthesis of the neurotransmitter acetylcholine. Compounds of this sort may prove to be useful drugs for the treatment of neurodegenerative diseases such as Alzheimer’s disease.arrow_forwardPredict the major products of the following base-catalyzed aldol condensations withdehydration.(a) benzophenone (PhCOPh) + propionaldehydarrow_forward(a) Explain why an alkylamine is more basic than ammonia?(b) How would you convert(i) Aniline to nitrobenzene (ii) Aniline to iodobenzenearrow_forward
- The saccharide shown here is present in some plant-derived foods. (a) Indicate the anomeric carbon atom(s) in this structure by drawing a circle around the atom(s) or by drawing an arrow pointing to the atom(s). (b) Would this saccharide give a positive result with Benedict’s reagent? Why or why not? (c) Would this saccharide give a positive result with Barfoed’s reagent? Why or why not? (d) Would this saccharide give a positive result with Seliwanoff’s reagent? Why or why not? (e) In a separate set of experiments, the saccharide solution was treated with a reagent that breaks glycosidic bonds. After this treatment, would any of the three assays give different results? Be sure to indicate which assay results would be different and give a reason.arrow_forward(b) Give both the structures and IUPAC names of the reactants for the compound below formed via a crossed aldol reaction with KOH as promotor. Explain why only one product is formed:arrow_forwardPredict the major products of the following base-catalyzed aldol condensations withdehydration.(a) benzophenone (PhCOPh) + propionaldehydearrow_forward
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