Biology
Biology
5th Edition
ISBN: 9781260487947
Author: BROOKER
Publisher: MCG
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Chapter 23.2, Problem 3CC
Summary Introduction

To determine: The fate of frequencies of HA and HS alleles over the long run if malaria was completely eradicated.

Introduction: The prevalence of malaria depends on the homozygous and heterozygous nature of HA and HS alleles. In areas where malaria becomes endemic, population show homozygous nature for HA allele and depicts lower mean fitness.

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Suppose that a population is at equilibrium between mutation and selection for a deleterious recessive allele, where s = 0.5 and μ = 10−5. What is the equilibrium frequency of the allele? What is the selection cost?
Please answer fast Consider a laboratory population that consists entirely of individuals with the same“repulsion” double heterozygous (diploid) genotype, Ab/aB. Assume the rate ofrecombination between the “A” and “B” loci is c = 1/ 4 .a) What are r, s, t and u in this population? What is D?b) What are r, s, t and u after 1 generation of random breeding? What is D?c) What are r, s, t and u after 5 generations of random breeding? What is D?
for round  1. How many generations did it take for an allele to become fixed in the population? (See the number of generations on the X axis of your graph).  for wrinkled 2. How many generations did it take for an allele to become fixed in the population? (See the number of generations on the X axis of your graph).        Discuss the difference in the number of generations it took for your alleles to be fixed when you were selecting for round peas vs wrinkled peas. Which took more generations? How big was the difference? What do you think is the reason for this difference?
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