Chapter 26, Problem 26.15P

Interpretation Introduction

Interpretation:

Among, $\text{4-}$ bromopyridine or $3\text{-}$ bromopyridine, the one which should readily undergo substitution of the bromine by phenolate anion is to be stated with explanation. The structure of the product form is to be drawn.

Concept introduction:

The nucleophilic substitution reactions are the reactions in which one nucleophile is substituted by another nucleophile. These reactions depend upon the nucleophilicity and concentration of the nucleophile. There are two types of nuclephilic substitution reaction.

The ${\text{S}}_{\text{N}}2$ reaction is a nucleophilic substitution bimolecular single step reaction in which the addition of nucleophile and removal of leaving group takes place simultaneously.

The ${\text{S}}_{\text{N}}1$ reaction is a nucleophilic substitution reaction in which the substitution of nucleophile takes place. This reaction takes place in two steps. There is generation of carbocation in the first step and in the second step the nucleophile attacks at the carbocation for the corresponding product.