Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Chapter 4, Problem 3VCQ
Figure 4.18 If a peripheral membrane protein were synthesized in the lumen (inside) of the ER, would it end up on the inside or outside of the plasma membrane?
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Why is an ER signal sequence from a plasma membrane protein not sufficient to send a cytosolic protein to the plasma membrane?
The figure above shows the organization of a protein that will eventually reside in the
plasma membrane. The boxes labeled 1 and 2 represent membrane-spanning
sequences and the arrow represents a site of action of signal peptidase. Which of the
following statements must be TRUE about this protein?
O a) Most of this protein will project from the cytosolic side of the membrane.
O b) The mature version of this protein will span the membrane twice.
c) This is a multi-pass membrane protein.
O d) The mature version of this protein will span the membrane once.
Name and define (briefly) two of the different possible mechanisms of a plasma membrane proteins
Chapter 4 Solutions
Biology 2e
Ch. 4 - Figure 4.7 Prokaryotic cells are much smaller than...Ch. 4 - Figure 4.8 If the nucleolus were not able to carry...Ch. 4 - Figure 4.18 If a peripheral membrane protein were...Ch. 4 - When viewing a specimen through a light...Ch. 4 - The is the basic unit of life organism cell tissue...Ch. 4 - Prokaryotes depend on to obtain some materials and...Ch. 4 - Bacteria that lack fimbriae are less likely to...Ch. 4 - Which of the following organisms is a prokaryote?...Ch. 4 - Which of the following is surrounded by two...Ch. 4 - Peroxisomes got their name because hydrogen...
Ch. 4 - In plant cells, the function of the lysosomes is...Ch. 4 - Which of the following is both in eukaryotic and...Ch. 4 - Tay-Sachs disease is a genetic disorder that...Ch. 4 - Which of the following is not a component of the...Ch. 4 - The process by which a cell engulfs a foreign...Ch. 4 - Which of the following is most likely to have the...Ch. 4 - Which of the following sequences correctly lists...Ch. 4 - Congenital disorders of glycosylation are a...Ch. 4 - Which of the following have the ability to...Ch. 4 - Which of the following do not play a role in...Ch. 4 - In humans, are used to move a cell within its...Ch. 4 - Which of the following are only in plant cells?...Ch. 4 - The key components of desmosomes are cadherins...Ch. 4 - Diseased animal cells may produce molecules that...Ch. 4 - In your everyday life, you have probably noticed...Ch. 4 - In what situation(s) would the use of a scanning...Ch. 4 - In what situation(s) would a transmission electron...Ch. 4 - What are the advantages and disadvantages of each...Ch. 4 - Explain how the formation of an adult human...Ch. 4 - Antibiotics are medicines that are used to fight...Ch. 4 - Explain why not all microbes are harmful.Ch. 4 - You already know that ribosomes are abundant in...Ch. 4 - What are the structural and functional...Ch. 4 - Why are plasma membranes arranged as a bilayer...Ch. 4 - In the context of cell biology, what do we mean by...Ch. 4 - In your opinion, is the nuclear membrane part of...Ch. 4 - What are the similarities and differences between...Ch. 4 - How do cilia and flagella differ?Ch. 4 - Describe how microfilaments and microtubules are...Ch. 4 - Compare and contrast the boundaries that plant,...Ch. 4 - How does the structure of a plasmodesma differ...Ch. 4 - Explain how the extracellular matrix functions.Ch. 4 - Pathogenic E. coil have recently been shown to...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- [6.1] [6.2] If you could add channels to the membrane that make it permeable to peptides and water, what do you think would happen to the peptide and water molecules in the cell? If, after adding those channels, you were to wait long enough for the system to equilibrate (i.e., reach a stable state in which the number and type of molecule in each compartment no longer changes much over time), about how many peptide molecules would you expect to find on the left side of the cell and how many on the right? How about the water molecules? Explain your reasoning.arrow_forwardWhat type of signal sequence(s) would be used to create the ACE2 (type 1) integral membrane protein?arrow_forwardDescribe the difference between integral and peripheralproteins in the plasma membranearrow_forward
- Identify the three different types of membrane proteins.arrow_forwardWhat is the relationship between the Golgi apparatus and the ER in a protein-secreting cell?arrow_forwardThe rigidity of the plasma membrane is an essential characteristic that allows for cells to survive and thrive in various environments. What are examples of conditions or molecules that can alter plasma membrane rigidity?arrow_forward
- Can you list two different ways in which nucleotides can carry energy and draw a diagram of the cross-section of a typical plasma membrane?arrow_forwardIN the figure for D: The organization of a protein that normally resides in the plasma membrane in shown in the figure below. The boxes labeled 1,2 3 and 4 represent membrane-spanning sequences and the arrow represents a site of action of signal peptidase. Given this diagram, which of the following statements must be true? (C) (D) oplasmic Reticulum The N-terminus of this protein is in the ER lumen The mature version of this protein will span the membrane twice, with both the N- and C-terminus in the cytoplasm. Two of the answers are correct The C-terminus of this protein is in the ER lumenarrow_forwardWhat would happen in each of the following cases where something related to intracellular transport is altered? Assume in each case that the protein involved is a soluble protein, not a membrane protein. State where each protein would be located and explain each of your answers. You change the hydrophobic amino acids in an ER signal sequence into negatively charged amino acids. You discover a protein that has both an ER signal sequence and a nuclear localization sequence. The ER signal sequence is at the N-terminus of the protein, and the nuclear localization sequence is located in the middle of the protein.arrow_forward
- A peripheral protein, which is not integral to the cell membrane, is also called: a multi-pass transmembrane protein (like band 3.0 protein) a single-pass transmembrane protein (like glycophorin A) a monolayer-associated protein (like the COX-1 protein) a protein-attached protein (like cytochrome c) a lipid-linked protein (like the Ras protein)arrow_forwardYou are studying a hypothetical cell; during your observations you note that this cell is failing to successfully transport polypeptides across the ER membrane into the ER lumen. A physiological disfunction such as this would be deterimental to the viability of these cells. Suggest a possible cause for this failed transport and explain your reasoning.arrow_forwardWhat is the primary characteristic of peripheral membrane proteins? A: They cannot be post-translationally modified. B: They span the entire lipid bilayer, sometimes multiple times. C: Detergents or nonpolar solvents are necessary to remove them from the lipid bilayer. D:Weak intermolecular forces keep them attached to the lipid membrane.arrow_forward
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