Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 5, Problem 32CTQ
The sodium/calcium exchanger (NCX) transports sodium into and calcium out of cardiac muscle cells. Describe why this transporter is classified as secondary active transport.
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the sodium channel exchanger NCX transports sodium into and calcium out of cardiac muscle cells. Describe why this itransporter is classified as secondary active transport?
In all human cells, there is a higher concentration of calcium ions outside of thecell than on the inside of the cell. Calcium pumps are primary active transportproteins that help to maintain this imbalance. Describe how calcium pumpswork, including the direction of ion transport and the source of energy of thecalcium pumps.
If a skeletal muscle has depleted its stores of ATP how will the altered transport properties of the
following transporters affect cytosolic ion concentrations (increase, decrease, no change)
relative to normal?
Skeletal Muscle Cell With Depleted ATP Stores
Ion transporter
Cytosolic K+
Cytosolic Na+
Cytosolic Ca2+
NKA
NCX
SERCA
Chapter 5 Solutions
Biology 2e
Ch. 5 - Figure 5.12 A doctor injects a patient with what...Ch. 5 - Figure 5.16 Injecting a potassium solution into a...Ch. 5 - Figure 5.19 If the pH outside the cell decreases,...Ch. 5 - Which plasma membrane component can be either...Ch. 5 - Which characteristic of a phospholipid contributes...Ch. 5 - What is the primary function of carbohydrates...Ch. 5 - A scientist compares the plasma membrane...Ch. 5 - Water moves via osmosis. throughout the cytoplasm...Ch. 5 - The principal force driving movement in diffusion...Ch. 5 - What problem is faced by organisms that live in...
Ch. 5 - In which situation would passive transport not use...Ch. 5 - Active transport must function continuously...Ch. 5 - How does the sodium-potassium pump make the...Ch. 5 - What is the combination of an electrical gradient...Ch. 5 - What happens to the membrane of a vesicle after...Ch. 5 - Which transport mechanism can bring whole cells...Ch. 5 - In what important way does receptor-mediated...Ch. 5 - Many viruses enter host cells through receptor-...Ch. 5 - Which of the following organelles relies on...Ch. 5 - Imagine a cell can perform exocytosis, but only...Ch. 5 - Why is it advantageous for the cell membrane to be...Ch. 5 - Why do phospholipids rend to spontaneously orient...Ch. 5 - How can a cell use an extracellular peripheral...Ch. 5 - Discuss why the following affect the rate of...Ch. 5 - Why does water move through a membrane?Ch. 5 - Both of the regular intravenous solutions...Ch. 5 - Describe two ways that decreasing temperature...Ch. 5 - A cell develops a mutation in its potassium...Ch. 5 - Where does the cell get energy for active...Ch. 5 - How does the sodium-potassium pump contribute to...Ch. 5 - Glucose from digested food enters intestinal...Ch. 5 - The sodium/calcium exchanger (NCX) transports...Ch. 5 - Why is it important that there are different types...Ch. 5 - Why do ions have a difficult time getting through...
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- List the means of unassisted membrane transport.arrow_forwardDescribe the contribution of each of the following to establishing and maintaining membrane potential: (a) the Na+K+ pump, (b) passive movement of K+ across the membrane, (c) passive movement of Na+ across the membrane, and (d) the large intracellular anions.arrow_forwarda skeletal muscle cell has depleted its stores of ATP how will the altered transport properties of the NKA transporter affect cytosolic calcium concentrations (increase, decrease, no change) relative to normal? Why?arrow_forward
- The contraction of cardiac muscle cells results from the increase in calcium ion levels in the cytosol. For the cells to relax, an antiport removes calcium ion from the cytosol for every sodium ion that is taken in. Digitalis is a drug that is used to make the heart contract more strongly. This drug partially inhibits the Na+-K+ ATPase in the cardiac cells. Applying the concepts about membrane transport, answer the following: a. Propose an explanation for the drug’s effect.b. What will likely happen if too much of the drug is taken in? Why?arrow_forwardThe contraction of cardiac muscle cells results from the increase in Ca?+ levels in the cytosol. For these cells to relax, an antiport removes Ca?+ from the cytosol for every Nat that is taken in. Digitalis is a drug that is used to make the heart contract more strongly. This drug partially inhibits the Na*-K* ATPase in the cardiac cells. Applying the concepts from membrane transport, answer the following: a. Propose an explanation for the drug's effect. b. What will likely happen if too much of the drug is taken in? Why do you say so?arrow_forwardBelow find the structures for ibogaine and cocaine. Ibogaine and cocaine inhibit the dopamine active transporter (DAT). This transporter is a secondary active transporter, and depends on the primary active transporter Na+/K+ ATPase. Ibogaine had a Kι = 2 μM, and cocaine a Kι = 0.64 μM respectively. (a) Define secondary active transport. (b) Is ibogaine an effective treatment for cocaine based on DAT binding?arrow_forward
- Compare and contrast simple transporters, thephosphotransferase system, and ABC transporters in terms of(1) energy source, (2) chemical alterations of the solute duringtransport, and (3) number of proteins requiredarrow_forwardThe sodium-calcium-exchanger (NCX) protein is an antiport protein that is located in the membranes of cardiac muscle cells in humans as well as other cells. Antiport proteins transport two different solutes in opposite directions. The sodium-calcium-exchanger protein functions by secondary active transport and requires the sodium-potassium pump in order to function. The sodium-potassium pump functions by primary active transport and transports sodium ions from the intracellular fluid to the extracellular fluid. • Describe how the sodium-potassium pump provides energy for the function of the sodium-calcium-exchanger. Considering that the NCX protein is an antiport protein, describe the concentration gradient of calcium on both sides of the cell membrane. Describe the direction that the calcium ions are transported.arrow_forwardName the three classes of membrane transport proteins. Explain which one or ones of these classes is able to move glucose and which can move bicarbonate (HCO3−) against an electrochemical gradient. In the case of bicarbonate, but not glucose, the ΔG of the transport process has two terms. What are these two terms, and why does the second not apply to glucose? Why are cotransporters often referred to as examples of secondary active transport?arrow_forward
- the maximal rate of solute movement during diffusion is greater than during mediated transport true or false?arrow_forward"Transporters saturate at high concentrations of the transported molecule when all their binding sites are occupied; channels, on the other hand, do not bind the ions they transport and thus the flux of ions through a channel does not saturate." is true or false.arrow_forwardName the three types of carrier proteins. Which of these can mediate secondary active transport?arrow_forward
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