Below is the structure of a hypothetical photo-affinity probe analogue of the anti- malarial drug artemisinin: A C H. H'HN- artemisinin photoaffinity probe Match the regions A, B, and C as indicated in the structure with their role in the photoaffinity labeling experiment Cross-links with nearby proteins in [ Choose ] the presence of UV light Allows for identifying/isolating ("fishing") the protein-probe adduct out of a complex mixture [ Choose ] Non-covalently binds to the same [ Choose ] protein target as artemisinin would have

Below is the structure of a hypothetical photo-affinity probe analogue of the anti- malarial drug artemisinin: A C H. H'HN- artemisinin photoaffinity probe Match the regions A, B, and C as indicated in the structure with their role in the photoaffinity labeling experiment Cross-links with nearby proteins in [ Choose ] the presence of UV light Allows for identifying/isolating ("fishing") the protein-probe adduct out of a complex mixture [ Choose ] Non-covalently binds to the same [ Choose ] protein target as artemisinin would have

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter3: Stereoisomerism And Chirality

Section3.8: The Significance Of Chirality In The Biological World

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