Concept explainers
(a)
Interpretation:
The substituted
Concept introduction:
In the Heck reaction, the palladium-catalyzed coupling of an aryl or vinyl halide with an alkene to give a new carbon-carbon bond at the less substituted end of the alkene, that are generally with trans stereochemistry.
This reaction is used in the drug synthesis; the palladium catalysts can be recovered and recycled.
(b)
Interpretation:
The substituted alkene that is used in the Heck reaction to make the given products is to be stated.
Concept introduction:
In the Heck reaction, the palladium-catalyzed coupling of an aryl or vinyl halide with an alkene to give a new carbon-carbon bond at the less substituted end of the alkene, that are generally with trans stereochemistry.
This reaction is used in the drug synthesis; the palladium catalysts can be recovered and recycled.
Want to see the full answer?
Check out a sample textbook solutionChapter 17 Solutions
Organic Chemistry (9th Edition)
- Draw the organic product you would expect to isolate from the nucleophilic substitution reaction between the molecules shown. Note: You do not need to draw any of the side products of the reaction, only the substitution product. H × 5 Br + HO + 1 Click and drag to start drawing a structure.arrow_forward2. The following carbocation is generated as an intermediate in the addition of H-Br to an alkene. Draw the structure of all possible alkenes that could have formed this intermediate.arrow_forwardComplete the reaction by providing the starting material/reagent/products. Match each item to a choice: HO OH NO₂ Cl₂ FeCl3 HO SO3 conc. H₂SO4 KMnO4 H₂O NO₂ NO₂ CIarrow_forward
- #16g. Provide the missing reactants, reagents, or products for the following reaction sequences below.arrow_forwardWhat explains why many aldehydes and ketones can undergo self- condensation reactions in basic conditions? The alpha carbon can lose a proton and act like a nucleophile and the carbonyl carbon a an electrophile O The alpha carbon can gain a proton and act like an electrophile and the carbonyl carbon is a nucleophile O The oxygen of the carbonyl group can attack the carbon of the carbonyl group Only esters can undergo self-condensation reactionsarrow_forwardHow could the following compounds be prepared using an alkene as one of the starting materials?arrow_forward
- Draw the organic product you would expect to isolate from the nucleophilic substitution reaction between the molecules shown. Note: You do not need to draw any of the side products of the reaction, only the substitution product. OH- 0 + I X Click and drag to start drawing a structure.arrow_forwardA. REACTIONS OF ALKENES- provide the product(s) or reagents that are needed to accomplish the following transformations CH3 1. BH 3, THF 2. H₂O₂, NaOH, H₂Oarrow_forward1c. What is the nucleophile in the following reaction? .Br CH;CO0 Na LO OCCH3 NaBr ld. What is the electrophile in the following reaction? Br CH;COO Na L0OCCH3 NaBr +arrow_forward
- what are some EXAMPLES of chemical compounds that are FORMED using the Heck reaction by forming a C-C bond with an aryl halide and an alkene? (name the chemical compounds)arrow_forwardComplete the reaction by providing the starting material/reagent/products. Match each item to a choice: CI Cl₂ FeCl3 HO OH NO₂ for HO NO₂ O SO3 conc. H₂SO4 NO₂ KMnO4 H₂Oarrow_forwardCarbenes can add to alkenes to give a cyclopropane derivative. Draw the alkene (unknown X) that reacts with the carbene to give the following product. X +arrow_forward
- ChemistryChemistryISBN:9781305957404Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCostePublisher:Cengage LearningChemistryChemistryISBN:9781259911156Author:Raymond Chang Dr., Jason Overby ProfessorPublisher:McGraw-Hill EducationPrinciples of Instrumental AnalysisChemistryISBN:9781305577213Author:Douglas A. Skoog, F. James Holler, Stanley R. CrouchPublisher:Cengage Learning
- Organic ChemistryChemistryISBN:9780078021558Author:Janice Gorzynski Smith Dr.Publisher:McGraw-Hill EducationChemistry: Principles and ReactionsChemistryISBN:9781305079373Author:William L. Masterton, Cecile N. HurleyPublisher:Cengage LearningElementary Principles of Chemical Processes, Bind...ChemistryISBN:9781118431221Author:Richard M. Felder, Ronald W. Rousseau, Lisa G. BullardPublisher:WILEY