Organic Chemistry
Organic Chemistry
6th Edition
ISBN: 9781936221349
Author: Marc Loudon, Jim Parise
Publisher: W. H. Freeman
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Chapter 21, Problem 21.61AP
Interpretation Introduction

Interpretation:

The compound A in the given reaction is to be identified. The curved-arrow mechanism for the conversion of compound A to -caprolactum is to be predicted.

Concept introduction:

Oxime belongs to the family of imines. The formula of oxime is RRC=NOH. Types of oxime are ketoxime and aldoxime. The reaction proceeds through a nucleophilic addition reaction. The catalyst acts as a nucleophile in the reaction.

The process by which respective monomers combine to form polymers is known as polymerization. The polymer -caprolactum is nylon -6. The polymers can be prepared by addition and condensation reactions. Synthetic polymers are categorized as chain-growth or step-growth polymers.

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Safrole, which is isolated from sassafras (Problem 21.33), can be converted to the illegal stimulant MDMA (3,4- methylenedioxymethamphetamine, “Ecstasy”) by a variety of methods. (a) Devise a synthesis that begins with safrole and uses a nucleophilic substitution reaction to introduce the amine. (b) Devise a synthesis that begins with safrole and uses reductive amination to introduce the amine.
Safrole, which is isolated from sassafras (Problem 21.33), can be converted to the illegal stimulant MDMA (3,4-methylenedioxymethamphetamine, "Ecstasy") by a variety of methods. (a) Devise a synthesis that begins with safrole and uses a nucleophilic substitution reaction to introduce the amine. (b) Devise a synthesis that begins with safrole and uses reductive amination to introduce the amine. NHCH9 MDMA safrole
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